Micro-synthesis and electron ionization mass spectral analysis of O-alkyl N,N-dialkylphosphoramidocyanidates

Eur. J. Mass Spectrom. 11, 309–318 (2005)
DOI: 10.1255/ejms.741

Micro-synthesis and electron ionization mass spectral analysis of O-alkyl N,N-dialkylphosphoramidocyanidates

Arvind. K. Gupta, Meehir Palit, Deepak Pardasani, Purushottam Shakya, Rajendra K. Srivastava and Devendra K. Dubey^*
Vertox Laboratory, Defence Research and Development Establishment, Gwalior, India. E-mail: dkdubey@rediffmail.com

ABSTRACT:

This communication describes microsynthesis and GC/MS analysis of O– alkyl N,N-dialkylphosphoramidocyanidates (ADAPCs), which are analogues of chemical warfare agent, Tabun. The study was undertaken with a view to develop spectral data base of ADAPCs for verification purpose of Chemical Weapons Convention (CWC). Reported microsynthetic approach has advantages over traditional synthesis in terms of efficiency, synthetic waste, and exposure to toxic chemicals. GC/MS analysis of variety of these compounds (ADAPCs) was performed. Based on the obtained mass spectra of structurally diverse ADAPCs, the fragmentation routes are proposed, which explains most of the characteristic ions.

Keywords: chemical warfare agents, chemical weapons convention, verification, tabun, nerve agents, microsynthesis

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