|
Eur. J. Mass Spectrom. 1, 539 - 543 (1995) |
|
Acetone chemical ionization studies. VIII: pyridine derivatives | ||
M. Vairamani,* S. Prabhakar, N. Prasada Raju and G.K. Viswanadha Rao |
||
ABSTRACT: | ||
Acetone chemical ionization mass spectra of pyridine and 23 isomeric alkyl, dialkyl, amino, hydroxy, cyano and halo pyridines were studied. The formation of [M + H]+ ions and the adducts corresponding to [M + 43]+and [M + 59]+ ions is controlled by the proton affinity of the substrate and the position of the substituent. The acetylation reaction is less pronounced in 2-substituted pyridines due to steric factors, except in amino and hydroxypyridines where the acetylated ion is stabilized through hydrogen bonding. Collision-induced dissociation (CID) spectra of [M + 43]+ ions of isomeric amino and hydroxypyridines suggest acetylation occurs mainly at the ring nitrogen. | ||
Keywords: |
You can now buy this paper on-line in PDF format; it costs only £11.75. Just click on the BUY on-line button. You can pay on-line through a secure server and get access immediately.
© IM Publications
Any problems? E-mail .