|
Eur. J. Mass Spectrom. 3, 339 - 346 (1997) |
|
The gas-phase basicities of matrix-assisted laser desorption/ionization matrices | ||
R.J.J.M. Steenvoorden, K. Breuker and R. Zenobi* |
||
ABSTRACT: | ||
The gas-phase basicities of three common matrices used in matrix-assisted laser desorption/ionization (MALDI) have been investigated using laser desorption with Fourier transform ion cyclotron resonance (FT-ICR) mass spectrometry. In bracketing type experiments, laser-desorbed ions from 2,5-dihydroxy-benzoic acid, a-cyano-4-hydroxy-cinnamic acid and sinapic acid were tested for their ability to protonate test substances. This study was not limited to protonated matrix species but also included prominent fragments. | ||
Keywords: MALDI, FT-ICR, proton affinity, fragmentation, matrix |
© IM Publications
Any problems? E-mail .