Full-text Article (Subscribers only)
Full-text article (255 kB)
(subscribers only)

Buy article on-line and get access immediately
Buy article on-line for £11.75
(get immediate access)

Search
Search

Go Back

Eur. J. Mass Spectrom. 8, 79 - 84 (2002)

Polymer track membranes for extraction of ions from aqueous solutions at atmospheric pressure

Alexander. A. Balakin,* Alexander F. Dodonov, Mikhail I. Markin, Lyudmila I. Novikova, Ilia V. Soulimenkov and Victor L. Talroze<
Institute for Energy Problems of Chemical Physics, Russian Academy of Sciences, 142432 Chernogolovka, Moscow region, Russia. E-mail:
Bogdan A. Budnik, Kim F. Haselmann and Roman A. Zubarev
University of Southern Denmark, DK-5230 Odense M, Denmark

ABSTRACT:
The possibility of the application of the electromembrane technique for production of ions of biological molecules at atmospheric pressure is demonstrated. This technique has previously only been used for extraction of ions from liquids directly into vacuum. The membrane technique for ion extraction at atmospheric pressure was tested with both time-of-flight and Fourier transform ion cyclotron resonance mass spectrometers. The mass spectra of intact molecular ions obtained from aqueous solutions of peptides and proteins are presented. The possible mechanisms of non-destructive ion extraction are discussed. The new technique is promising for achieving absolute sensitivity (charging every analyte molecule) and for performing spatially-resolved analysis of liquid biological samples.

Keywords: ion extraction from solutions, track membranes, mass spectrometric analysis of polypeptides

You can now buy this paper on-line in PDF format; it costs only £11.75. Just click on the BUY on-line button. You can pay on-line through a secure server and get access immediately.


© IM Publications
Any problems? E-mail .