Mass spectrometry study of acylthioureas and acylthiocarbamates

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Eur. J. Mass Spectrom. DOI: 10.1255/ejms.511

Mass spectrometry study of acylthioureas and acylthiocarbamates

Roberto Martínez-Alvarez,^* Nazario Martín and Carlos Seoane
Departamento de Química Orgánica I, Facultad de Química, Universidad Complutense, E-28040 Madrid, Spain
Ana María Plutin, Margarita Suárez and Teresita Machado
Laboratorio de Síntesis Orgánica, Facultad de Química, Universidad de La Habana, 10400 Ciudad Habana, Cuba
Nour Kayali
Servicio de Espectrometría de Masas, Universidad Complutense, E-28040 Madrid, Spain

ABSTRACT:

A variety of acylthiocarbamates and acylthioureas have been investigated under electron impact ionization (EI), chemical ionization (CI) and electrospray ionization (ESI) conditions. Sequential product-ion fragmentation (MSⁿ) was performed to elucidate the degradation pathways for these compounds. Comparisons are made between positive and negative even-electron ions from ESI and CI and the odd-electron ions obtained under EI conditions. The data collected in this paper provide information on the strong differences found in the fragmentation process of these compounds.

Keywords: acylthiocarbamates; acylthoureas; electron impact; chemical ionization; electrospray; collision-induced dissociation

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