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Edited by Peter J. Derrick and Scott D. Paterson
This special issue of European Journal of Mass Spectrometry captures the state-of-the art with regard to analysis of peptides, proteins and their modifications by mass spectrometry, as it is applied to the broad field now referred to as “proteomics”.
The issue covers the analysis of proteins and peptides separated by 1D/2D gel- or capillary-electrophoresis and also non-gel approaches (e.g. chromatography-based). It will contain articles on methodological developments as well as innovative applications.
Paperback
Published: 2001
Pages: 145
Contents
Editorial: Mass spectrometry of proteomics
Peter J. Derrick and Scott D. Patterson
Toward efficient analysis of >70 kDa proteins with 100% sequence coverage
Andrew J. Forbes, Matthew T. Mazur, Neil L. Kelleher, Hiten M. Patel and Christopher T. Walsh
Gas-phase conformation can have an influence on peptide fragmentation
William J. Griffiths and Andreas P. Jonsson
Analysis of protein sequences and protein complexes by matrix-assisted laser desorption/ionization mass spectrometry
Maya Belghazi, Katell Bathany, Codjo Hountondji, Xavier Grandier-Vazeille, Stéphen Manon and Jean-Marie Schmitter
Simplified sample preparation method for protein identification by matrix-assisted laser desorption/ionization mass spectrometry: in-gel digestion on the probe surface
Allan Stensballe and Ole Nørregaard Jensen
Improved accuracy in the matrix-assisted laser desorption/ionisation mass spectrometry determination of the molecular mass of cyanogen bromide fragments of proteins by post-cleavage reaction with tris(hydroxymethyl)aminomethane
A. Compagnini, V. Cunsolo, S. Foti and R. Saletti
Limited acid hydrolysis as a means of fragmenting proteins isolated upon ProteinChip® Array surfaces
Shanhua Lin, Pete Tornatore, Scot R. Weinberger, Daniel King and Ron Orlando
Integrated system for high-throughput protein identification using a microfabricated device coupled to capillary electrophoresis/nanoelectrospray mass spectrometry
Jianjun Li, Tammy-Lynn Tremblay, Pierre Thibault, Can Wang, Said Attiya and D. Jed Harrison
Investigation of the applicability of a sequential digestion protocol using trypsin and leucine aminopeptidase M for protein identification by matrix-assisted laser desorption/ionization mass spectrometry
Alan Doucette and Liang Li
Multiple separations facilitate identification of protein variants by mass spectrometry
Zhongli Zhang, David L. Smith and Jean B. Smith
Mass spectrometric characterization of proteins extracted from Jurkat T cell detergent-resistant membrane domains
Priska D. von Haller, Sam Donohoe, Ruedi Aebersold, Julian D. Watts and David R. Goodlett
The effects of transcription regulating genes PDR1, pdr1-3 and PDR3 in pleiotropic drug resistance
Arkadiusz Nawrocki, Stephen J. Fey, Peter Mose Larsen, André Goffeau and Peter Roepstorff
Structural modifications of Methanococcus jannaschii flagellin proteins revealed by proteome analysis
Carol S. Giometti, Sandra L. Tollaksen, Gyorgy Babnigg, Claudia I. Reich, Gary J. Olsen, Hanjo Lim and John R. Yates, III
Detection and localisation of disulphide bonds in a synthetic peptide reproducing the sequence 1–30 of Par j 1.0101 by electrospray ionisation mass spectrometry
Vincenzo Cunsolo, Salvatore Foti, Rosaria Saletti, Leopoldo Ceraulo and Vita di Stefano
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